SARS-CoV-2, the virus that causes COVID-19, can cause lasting damage to energy production by mitochondria in many organs of the body. Source: SARS-CoV-2 can cause lasting damage to cells’ energy production
The coronavirus disease 2019 (COVID-19) pandemic represents one of the greatest threats to population health in more than a century. As of January 2023, >6.7 million deaths globally were attributed to COVID-19. As new mutations evolve, it is apparent that the virus will not be eliminated soon and that strategies for managing life with COVID-19 are needed.1A recent American Journal of Preventive Medicine study shows that exercise and exercise intensity have a strong impact onContinue…
Some patients who develop new cognitive symptoms after a mild bout of COVID-19 have abnormalities in their cerebrospinal fluid similar to those found in people with other infectious diseases. The finding may provide insights into how SARS-CoV-2 impacts the brain.In a small study with 32 adults, comprising 22 with cognitive symptoms and 10 control participants without, researchers from UC San Francisco and Weill Cornell Medicine, New York, analyzed the cerebrospinal fluid of 17 of theContinue…
Brain fog, memory loss, and other forms of cognitive dysfunction are common for those with Long COVID. To learn more, visit RTHM. Source: What Is “Brain Fog” and Cognitive Dysfunction in Long COVID?
Twelve people with persistent neurological symptoms after SARS-CoV-2 infection were intensely studied at the National Institutes of Health (NIH) and were found to have differences in their immune cell profiles and autonomic dysfunction. These data inform future studies to help explain persistent neurological symptoms in Long COVID. The findings, published in Neurology: Neuroimmunology & Neuroinflammation(link is external), may lead to better diagnoses and new treatments. Source: NIH study identifies features of Long COVID neurological symptomsContinue…
This meta-analysis of 41 studies that included a total of 860 783 patients demonstrates that there were certain epidemiologic and clinical risk factors that are associated with a higher risk of developing PCC. In particular, female sex, older age, higher BMI, and smoking were significantly associated with increased risk of persistent symptoms of 3 months or more after the acute phase of COVID-19 infection, ie, PCC. In addition, preexisting comorbidities, including anxiety and/or depression, asthma, COPD,Continue…
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection has been shown to be associated with a range of neurological complications during the acute and postacute phases.The pathogenesis of SARS-CoV-2-associated CNS disease is complex and diverse, and cannot be explained by one sole mechanism.To understand the pathogenesis of SARS-CoV-2-associated CNS disease, it is important to gain deeper insights into the neuroinvasiveness, neurotropism, and neurovirulence of SARS-CoV-2. It is also imperative to consider the kinetics, since a viralContinue…
#MillionsMissing 2023 will be held at the Washington Monument on the National Mall in Washington, DC on May 12th that will feature an art installation and press conference. This year, #MEAction in partnership with Body Politic, will host #MillionsMissing 2023 to demand bold, urgent governmental action for the millions of people living with myalgic encephalomyelitis (ME), Long COVID, and other infection-associated, complex-chronic diseases.Our protest will be an art installation that will have rows and rowsContinue…
The purpose of this Notice of Funding Opportunity (NOFO) is to promote basic research to better understand the mechanisms underlying viral invasion of the central nervous system (CNS), virus- and/or host immune-mediated neuropathogenesis, and the associated clinical manifestations for emerging and re-emerging neurotropic viruses. Source: RFA-AI-23-028: Fundamental Research to Understand the Mechanisms of Neurotropic Virus-mediated Disease (R01 Clinical Trial Not Allowed)
The specter of long COVID, with its mysterious cause, no obvious cure and an unknown duration, haunts millions and millions of people. In this report, we hear from some of those who are suffering with it and Wiliam Brangham speaks with Dr. David Putrino of Mount Sinai Health in New York about the varied symptoms people are dealing with.