ACE2-independent infection of T lymphocytes by SARS-CoV-2 | Signal Transduction and Targeted Therapy

Sars-Cov-2 and T Lymphocytes

SARS-CoV-2 induced marked lymphopenia in severe patients with COVID-19. However, whether lymphocytes are targets of viral infection is yet to be determined, although SARS-CoV-2 RNA or antigen has been identified in T cells from patients. Here, we confirmed that SARS-CoV-2 viral antigen could be detected in patient peripheral blood cells (PBCs) or postmortem lung T cells, and the infectious virus could also be detected from viral antigen-positive PBCs. We next prove that SARS-CoV-2 infects TContinue…

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Nevada man’s COVID-19 reinfection, the first in the US, is ‘yellow caution light’ about risk of coronavirus

A 25-year-old Nevada man is the first American confirmed to have been infected twice with COVID-19. He was sicker the second time.

Source: Nevada man’s COVID-19 reinfection, the first in the US, is ‘yellow caution light’ about risk of coronavirus